Jimmy - an eccentric and terminally ill young man - further loses touch with reality when he finds out that his best friend and roommate James is leaving for a new job tomorrow morning. Jimmy sees this as a betrayal of their perfect way of life, and over the course of a night full of drinks, drugs and women, the two men engage in a classic, humorous battle of wills as James prepares to enter the real world and Jimmy falls deeper and deeper into his world of illness, isolation, madness, and make-believe.